B-1 Cell Immunoglobulin Directed Against Oxidation-Specific Epitopes
نویسندگان
چکیده
منابع مشابه
B-1 Cell Immunoglobulin Directed Against Oxidation-Specific Epitopes
Natural antibodies (NAbs) are pre-existing antibodies with germline origin that arise in the absence of previous exposure to foreign antigens. NAbs are produced by B-1 lymphocytes and are primarily of the IgM isotype. There is accumulating evidence that - in addition to their role in antimicrobial host defense - NAbs exhibit important housekeeping functions by facilitating the non-immunogenic c...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2013
ISSN: 1664-3224
DOI: 10.3389/fimmu.2012.00415